What labeling warning is included on acetophenetidin?

What labeling warning is included on acetophenetidin?

• A. Kidney damage risk when used in large amounts or long-term; Do not exceed dosage or use longer than 10 days without consulting your physician
• B. Liver damage warning when alcohol is used
• C. No special warning
• D. May cause drowsiness

Answer: (A)

Acetophenetidin (phenacetin) carries a warning about kidney damage with prolonged or high-dose use. This drug is nephrotoxic, meaning it can cause kidney injury and analgesic nephropathy when used for extended periods or in large amounts. To help prevent this serious risk, labeling advises not to exceed the recommended dose and not to use the product for more than about 10 days without a physician’s guidance. The other warnings don’t fit this drug as closely: liver damage with alcohol is more associated with acetaminophen, and some statements like “no special warning” or “drowsiness” don’t reflect the principal safety concern for acetophenetidin.

Acetophenetidin (phenacetin) carries a warning about kidney damage with prolonged or high-dose use. This drug is nephrotoxic, meaning it can cause kidney injury and analgesic nephropathy when used for extended periods or in large amounts. To help prevent this serious risk, labeling advises not to exceed the recommended dose and not to use the product for more than about 10 days without a physician’s guidance. The other warnings don’t fit this drug as closely: liver damage with alcohol is more associated with acetaminophen, and some statements like “no special warning” or “drowsiness” don’t reflect the principal safety concern for acetophenetidin.