For Schedule III substances that are mixed with at least one active, non-narcotic ingredient, which is the maximum codeine content?

For Schedule III substances that are mixed with at least one active, non-narcotic ingredient, which is the maximum codeine content?

• A. ≤1.8 g/100 mL OR ≤90 mg/dosing unit
• B. ≤2.0 g/100 mL
• C. ≤5 mg/dosing unit
• D. ≤10 g/dosing unit

Answer: (A)

The main concept is the codeine content limit for Schedule III combination products that include a non-narcotic active ingredient. When codeine is mixed with at least one active non-narcotic ingredient, the product is classed as Schedule III and must keep codeine to no more than 90 mg per dosing unit and no more than 1.8 g per 100 mL (or per 100 g for solids). This means the maximum allowed codeine is either 90 mg in each dosing unit or 1.8 g in 100 mL/100 g of the product, whichever applies to the formulation. Among the options, the figure that matches both limits—1.8 g per 100 mL (or 100 g) and 90 mg per dosing unit—is the correct maximum. The other numbers either exceed the per-volume/per-weight cap or don’t align with the dosing-unit limit, so they’re not correct.

The main concept is the codeine content limit for Schedule III combination products that include a non-narcotic active ingredient. When codeine is mixed with at least one active non-narcotic ingredient, the product is classed as Schedule III and must keep codeine to no more than 90 mg per dosing unit and no more than 1.8 g per 100 mL (or per 100 g for solids). This means the maximum allowed codeine is either 90 mg in each dosing unit or 1.8 g in 100 mL/100 g of the product, whichever applies to the formulation. Among the options, the figure that matches both limits—1.8 g per 100 mL (or 100 g) and 90 mg per dosing unit—is the correct maximum. The other numbers either exceed the per-volume/per-weight cap or don’t align with the dosing-unit limit, so they’re not correct.